It happened late Saturday morning in the northbound lanes of the Northeast Extension (I-476) in Worcester Twp. between the Mid-County and Lansdale exits.
Police say a vehicle was stopped in the right lane of the multi-lane highway due to a flat
tire. Another driver stopped to help and pulled behind the car with its hazard lights on.
Police say a tanker truck carrying jet fuel was unable to stop in time and slammed into both vehicles, which caused a large fire.
The driver of the tanker truck and the driver of the second vehicle were both pronounced dead. The driver of the first vehicle with a flat tire was hospitalized for unknown injuries.
All lanes of the highway are shut down between those exits, and Turnpike officials expect them to be closed for an extended period of time.
Footage captured by passing motorist Hector Lucena shows the scene soon after the crash, as emergency services were arriving.
"My God, debris all over the place. What happened here?" Lucena says aloud in the video, before passing the burning tanker.