Sounds like a good time, only problem will be the heat. The Arizona desert is a remarkable place I ran around there for 8 yrs as a kid and never tired of it. If you are able to camp close to your prospecting areas it will be a huge advantage to be able to get back to camp to avoid the heat of midday. We used to go early in the morning and have a siesta until midafternoon then go back to our activity usually hunting or fishing. If you have four wheelers or at least one good 4x4 vehicle that will be a plus also. A satelite phone for emergencies is also adviseable, as are firearms or other means of protection, especially the farther south you go. Lots of people go into the desert for various activities, not all of them legal I might add. I for one would not go to far south without local guidance who knew the area and could be trusted completely. Always have enough water for 2 days or more within 5 minutes walk.
There are few dangerous spiders, scorpions will reside under rocks especially near water sources. Snakes are actually few and far between with several exceptions. It is entirely possible to stumble upon "nests" of rattlesnakes. I have done so 3 or 4 times in the 8 years I ran around there. If near water snakes come out at night and sit by the water waiting for prey. Skunks are common near water also at night, avoid as they may be rabid, same with coyotes, bobcats or cougars that don't run away at first sight of you. Have some method of towing disabled vehicles, a flat repair kit the kind with tire plugs is best and a 12v air compressor. If you drive in the washes or very dusty ground you may also get stuck, two vehicle buddy system is best. Shade hats are a must and clothing that protects you from the sun also. So, this is just a few things I advise, always use a buddy system and respect the sun and you will have a great experience